Assessment of immunity to the measles virus through the detection of IgG antibodies

Indrė Lipatova; Justina Dagytė; Algimantas Paulauskas

doi:10.6001/biologija.2025.71.3.3

Indrė Lipatova
Justina Dagytė
Algimantas Paulauskas

DOI: https://doi.org/10.6001/biologija.2025.71.3.3

Keywords: measles, IgG antibodies, serological detection

Abstract

Measles is a highly contagious viral infection that can lead to severe complications. The aim of this study was to evaluate immunity of the target population against the measles virus by assessing the presence of IgG antibodies. A total of 176 individuals were tested using the ELISA method. Fourteen participants (7.95%) were found to be non-immune, primarily from the 1976–1981 and 1982–1987 birth cohorts. The highest proportion of seronegative individuals (17.4%) was observed among those with unknown vaccination status. No significant differences were found between sexes. Most participants were from Kaunas, which also accounted for the majority of seronegative cases.